BB544: Toxicology A
Study Board of Science
Teaching language: Danish
EKA: N100027122, N100027112, N100027102
Assessment: Second examiner: None, Second examiner: External
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Autumn
Level: Bachelor
STADS ID (UVA): N100027101
ECTS value: 5
Date of Approval: 25-04-2019
Duration: 1 semester
Version: Archive
Comment
Entry requirements
Academic preconditions
Students taking the course are expected to:
- Have knowledge of scientific databases, academic oral presentations and basic laboratory skills
- Be able to use excel
Course introduction
The aim of the course is to introduce the student to fundamental toxicological terms, as well as the associated biochemical and physiological mechanisms. Design and analysis of basic toxicology experiments is introduced in the laboratory course at the end of the semester.
The course builds on the knowledge acquired in the courses FF500, FF503, BMB504, BMB530, SU514 and KE527.
For students admitted prior to 2012, the following courses apply: BB508, BMB501, BMB530, SU514, BMB504 and KE501
In relation to the competence profile of the degree it is the explicit focus of the course to:
- Give the competence to execute and analyse basic experiments within the field of toxicology.
- Give skills to read and interpret primary literature
- Give knowledge and understanding of the fundamental mechanisms behind toxicity in humans
Expected learning outcome
The learning objective of the course is that the student demonstrates the ability to:
- Analyse toxicokinetic data
- Describe the central organs and mechanisms involved in human xenobiotic metabolism.
- Present scientific material in a structured and well formulated manner.
Content
Literature
Pharmaceutical Toxicology af Mulder og Dencker
See Blackboard for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam a)
Timing
Autumn
Tests
Active participation during the course (risk assesment, flowcharts, oral presentation, etc.)
EKA
N100027122
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
0
Additional information
The prerequisite examination is a prerequisite for participation in exam element a)
Prerequisites for participating in the exam b)
Timing
Autumn
Tests
Present during at least 80% of the laboratory course
EKA
N100027112
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
0
Additional information
The prerequisite examination is a prerequisite for participation in exam element a)
Exam element a)
Timing
January
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam b) | N100027101, BB544: Toxicology A |
Tests
Written exam
EKA
N100027102
Assessment
Second examiner: External
Grading
7-point grading scale
Identification
Student Identification Card
Language
Normally, the same as teaching language
Examination aids
Not allowed, a closer description of the exam rules will be posted under 'Course Information' on Blackboard.
ECTS value
5
Additional information
The examination form for re-examination may be different from the exam form at the regular exam.
Indicative number of lessons
Teaching Method
At the faculty of science, teaching is organized after the three-phase model ie. intro, training and study phase.
The lectures primarily concern the contents of the book, which is associated with this course. Each of the chapters are examined and explained, with focus on the topics at hand, as well as the background for these topics. Should the topic of the day concern liver toxicants, the basic layout and function of the liver is also presented. This understanding of each organ, cell type or tissue is used to put toxic effects of pharmaceuticals in to a context. The context of this course is essentially the human body, and its response to toxicants.
In the three first tutorial classes, we spend half of the time listening to, and discussion, student presentations of primary research literature from various toxicology journals. The other half we spend with relevant questions about each topic in the book. There will be a focus on questions that are relevant to the examination at the end of the course. In the two final tutorial classes, I will present the laboratory exercises and the background of these, we will then train the essential calculation skills needed for the laboratory course.
During the laboratory course, students are asked to perform risk assessment/evaluation on the experiments they are going to perform, using a guide that has been developed by the Department of Biology. They are furthermore asked to produce flowcharts for every experiment, before starting the practical work.
The final day of the laboratory course will be spent presenting the results from the laboratory course and evaluating.
Teacher responsible
| Name | Department | |
|---|---|---|
| Johannes Lørup Buch | jbuch@biology.sdu.dk | Biologisk Institut |
| Katrine Hulgard | khulgard@biology.sdu.dk | Biologisk Institut |