SU519: Module 4. Physiology and Pharmacology for Pharmacists: Hormones, glands, bones and nervous system
Comment
Entry requirements
Academic preconditions
Course introduction
of the nervous system and the endocrine organs under normal
physiological conditions and in disease. This is important for being
able to explain the effect of a pharmacological treatment directed to
these organs under normal physiological conditions and in disease.
course is based on the knowledge acquired in module 1 to 3, i.e. SU516,
SU517, and SU518 and provides a scientific basis for studying the
course on Clinical pharmacology and therapeutics, which will be taught
in the master's program.
- combine
the various disciplines in the natural sciences with the more
application-oriented medical disciplines, in particular for resolving
pharmacological problems and for the development of new drugs
- acquire new knowledge effectively and independently and apply this knowledge in a critical way.
- perform analyzes using scientific methodology
- identify own deficits in knowledge and to structure own learning
- the theories and methods within the discipline
- knowledge acquisition and experimental methods in the pharmaceutical sciences and related fields.
Expected learning outcome
- Understand and apply physiological terms and concepts properly for future studies.
- Describe the anatomy of hypothalamus, pituitary gland, thyreoida gland, adrenal gland, and bones
- Understand
the physiological regulation of the hypothalamus-pituitary
gland-endocrine gland axes. To understand how diseases affect the axes.
Identify therapeutic targets and examples hereof. - Understand how
the organism regulates calcium and phosphate balance including bone
remodeling under normal physiological situation and pathophysiological
conditions. Identify therapeutic targets and examples hereof. - Describe the gross anatomy of the nervous system.
- Describe the cellular organization of the nervous system and the general functions of neurons and glial cells.
- Describe the meningues and CNS blood supply.
- Describe the cerebrospinal fluid production circulation and function.
- Describe the make-up and function of the blood brain barrier
- Understand the electrochemical properties of neurons, incl. initiation and propagation of action potentials (nerve impulses).
- Understand
signal transduction in the synapse, incl. transmitter functions and
possibilities for modulation of signal transmission. - Understand spinal cord and the neuronal basis for most important reflexes.
- Understand
the peripheral somatosensory and visceral sensory receptors,
propagation of somatosensory information from the periphery to the
cerebral cortex. - Understand the senses (vision, hearing,
balance, taste, smell) and the how they are connected to the cerebral
cortex and sense reflexes. - Understand the structural and functional organization of the motor pathways from cerebral cortex to muscle.
- Describe the functional interaction between primary cortical motor areas and other cortical areas.
- Understand the structural and functional organization of the basal ganglia and connected brain areas.
- Understand the structural and functional organization of the cerebellum.
- Describe
the structural and functional organization of the cerebral cortex the
neural background for consciousness, sleep and arousal. - Describe cognitive functions, incl. language, perception of space, self and personality.
- Understand
the structural and functional organization of the limbic system, the
neural basis for emotions, motivation, learning and memory.
Content
- Endocrinology, anatomy of the endocrine glands, physiological regulation and pharmacological targets
- Macro and micro anatomy of the nervous system, basal neurophysiology and neurotransmission
- Menigues, blood vessels in the brain and cerebrospinal fluid circulation
- The function of the blood brain barrier
- The structure and function of the spinal cord, cranial nerves with a focus on reflexes, sensory and motor pathways
- Sensory systems, including vision, hearing, balance, smell and taste
- Motor systems including basal ganglia and cerebellum
- The limbic system, emotions, learning and memory
- Structure and organization of the cerebral cortex
- Cortical functions: wakefulness and sleep
Literature
Physiology 6th Edition, By Linda S. Constanzo
Rang and Dale’s Pharmacology, 8th Edition
Supplemented with additional material for neuro.
See Blackboard for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam element a)
Timing
Tests
Introduction and presentation of case
EKA
Assessment
Grading
Identification
Language
Examination aids
To be announced during the course
ECTS value
Additional information
The prerequisite examination is a prerequisite for participation in exam element a)
Exam element a)
Timing
Prerequisites
Type | Prerequisite name | Prerequisite course |
---|---|---|
Prerequisite not found |
Tests
Written exam
EKA
Assessment
Grading
Identification
Language
Duration
Examination aids
To be announced during the course
ECTS value
Additional information
Indicative number of lessons
Teaching Method
The introduction phase consists of lectures, in which the students will get a brief introduction to the course topics and the way to achieve competences. This will be complemented by the study guide and the textbooks, which the students are expected to study independently.
During the training phase, the students will achieve competences in endocrinology and neurobiology (anatomy, physiology and pharmacology). In the small classroom teaching, the students will work with assignments, which they will have to prepare at home. In the study phase, students are expected to work independently with textbooks and examples and exercises herein. They are expected to work in small groups as regards elaboration and presentation of “case” work. Finally, students are expected to use part of the study phase to work on assignments of the training phase and do some repetition for the written exam.
Activities during the studyphase:
- Self-study of the textbook
- Self-study after the introduction and training phase
- Repetition in preparation of the exam