SU519: Module 4. Physiology and Pharmacology for Pharmacists: Hormones, glands, bones and nervous system

Study Board Pharmacy

Teaching language: Danish or English depending on the teacher
EKA: N560021112, N560021102
Assessment: Second examiner: None, Second examiner: Internal
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Spring
Level: Bachelor

STADS ID (UVA): N560021101
ECTS value: 5

Date of Approval: 07-11-2018


Duration: 1 semester

Version: Archive

Comment

29004701(former UVA) is identical with this course description. 

Entry requirements

None

Academic preconditions

Students taking the course are expected to: Have knowledge of the basics of physics, chemistry and biochemistry.

Course introduction

The aim of the course is to give students insight into the function
of the nervous system and the endocrine organs under normal
physiological conditions and in disease. This is important for being
able to explain the effect of a pharmacological treatment directed to
these organs under normal physiological conditions and in disease. 

The
course is based on the knowledge acquired in module 1 to 3, i.e. SU516,
SU517, and SU518 and provides a scientific basis for studying the
course on Clinical pharmacology and therapeutics, which will be taught
in the master's program.

With regard to the competence profile of the curriculum, it is the explicit focus of the course to:

Provide the competence to:
  • combine
    the various disciplines in the natural sciences with the more
    application-oriented medical disciplines, in particular for resolving
    pharmacological problems and for the development of new drugs 
Provide skills to: 
  • acquire new knowledge effectively and independently and apply this knowledge in a critical way.
  • perform analyzes using scientific methodology
  • identify own deficits in knowledge and to structure own learning
Provide knowledge about:
  • the theories and methods within the discipline
  • knowledge acquisition and experimental methods in the pharmaceutical sciences and related fields.

Expected learning outcome

The learning objective of the course is that the student demonstrates the ability to:

  • Understand and apply physiological terms and concepts properly for future studies.
  • Describe the anatomy of hypothalamus, pituitary gland, thyreoida gland, adrenal gland, and bones
  • Understand
    the physiological regulation of the hypothalamus-pituitary
    gland-endocrine gland axes. To understand how diseases affect the axes.
    Identify therapeutic targets and examples hereof.
  • Understand how
    the organism regulates calcium and phosphate balance including bone
    remodeling under normal physiological situation and pathophysiological
    conditions. Identify therapeutic targets and examples hereof.
  • Describe the gross anatomy of the nervous system.
  • Describe the cellular organization of the nervous system and the general functions of neurons and glial cells.
  • Describe the meningues and CNS blood supply.
  • Describe the cerebrospinal fluid production circulation and function.
  • Describe the make-up and function of the blood brain barrier
  • Understand the electrochemical properties of neurons, incl. initiation and propagation of action potentials (nerve impulses).
  • Understand
    signal transduction in the synapse, incl. transmitter functions and
    possibilities for modulation of signal transmission.
  • Understand spinal cord and the neuronal basis for most important reflexes.
  • Understand
    the peripheral somatosensory and visceral sensory receptors,
    propagation of somatosensory information from the periphery to the
    cerebral cortex. 
  • Understand the senses (vision, hearing,
    balance, taste, smell) and the how they are connected to the  cerebral
    cortex and  sense reflexes.
  • Understand the structural and functional organization of the motor pathways from cerebral cortex to muscle.
  • Describe the functional interaction between primary cortical motor areas and other cortical areas.
  • Understand the structural and functional organization of the basal ganglia and connected brain areas.
  • Understand the structural and functional organization of the cerebellum.
  • Describe
    the structural and functional organization of the cerebral cortex the
    neural background for consciousness, sleep and arousal.
  • Describe cognitive functions, incl. language, perception of space, self and personality.
  • Understand
    the structural and functional organization of the limbic system, the
    neural basis for emotions, motivation, learning and memory.

Content

The following main topics are taught in the course: 
  • Endocrinology, anatomy of the endocrine glands, physiological regulation and pharmacological targets
  • Macro and micro anatomy of the nervous system, basal neurophysiology and neurotransmission
  • Menigues, blood vessels in the brain and cerebrospinal fluid circulation
  • The function of the blood brain barrier
  • The structure and function of the spinal cord, cranial nerves with a focus on reflexes, sensory and motor pathways
  • Sensory systems, including vision, hearing, balance, smell and taste
  • Motor systems including basal ganglia and cerebellum
  • The limbic system, emotions, learning and memory
  • Structure and organization of the cerebral cortex
  • Cortical functions: wakefulness and sleep

Literature

Physiology 6th Edition, By Linda S. Constanzo
Rang and Dale’s Pharmacology, 8th Edition
Supplemented with additional material for neuro.
See Blackboard for syllabus lists and additional literature references.

Examination regulations

Prerequisites for participating in the exam element a)

Timing

Spring

Tests

Introduction and presentation of case

EKA

N560021112

Assessment

Second examiner: None

Grading

Pass/Fail

Identification

Student Identification Card

Language

Normally, the same as teaching language

Examination aids

To be announced during the course

ECTS value

0

Additional information

The prerequisite examination is a prerequisite for participation in exam element a)

Exam element a)

Timing

June

Prerequisites

Type Prerequisite name Prerequisite course
Prerequisite not found

Tests

Written exam

EKA

N560021102

Assessment

Second examiner: Internal

Grading

7-point grading scale

Identification

Student Identification Card

Language

Normally, the same as teaching language

Duration

4 hours

Examination aids

To be announced during the course

ECTS value

5

Additional information

The examination form for re-examination may be different from the exam form at the regular exam.

Indicative number of lessons

43 hours per semester

Teaching Method

The introduction phase consists of lectures, in which the students will get a brief introduction to the course topics and the way to achieve competences. This will be complemented by the study guide and the textbooks, which the students are expected to study independently.

During the training phase, the students will achieve competences in endocrinology and neurobiology (anatomy, physiology and pharmacology). In the small classroom teaching, the students will work with assignments, which they will have to prepare at home. In the study phase, students are expected to work independently with textbooks and examples and exercises herein. They are expected to work in small groups as regards elaboration and presentation of “case” work. Finally, students are expected to use part of the study phase to work on assignments of the training phase and do some repetition for the written exam.

Activities during the studyphase:

  • Self-study of the textbook
  • Self-study after the introduction and training phase
  • Repetition in preparation of the exam

Teacher responsible

Name E-mail Department
Åsa Fex Svenningsen aasvenningsen@health.sdu.dk

Timetable

Administrative Unit

Fysik, kemi og Farmaci

Team at Educational Law & Registration

NAT

Offered in

Odense

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