BMB512: Teoretical Immunology
Comment
Entry requirements
Academic preconditions
Course introduction
The course builds on the knowledge acquired in the courses BMB532 and BMB533 and gives an academic basis for studying the topic infection and immunity, as well as pathophysiology.
In relation to the competence profile of the degree it is the explicit focus of the course to:
- Give skills to interpret and evaluate current scientific literature in immunology at a basic level.
- Give knowledge and understanding of basic immunological mechanisms.
Expected learning outcome
- describe the structure and individual elements of the innate and the adaptive immune system.
- explain the recognition mechanisms of the innate immune system and the consequences of its activation
- Explain the inflammatory response and describe the function of the key cytokines
- Explain the genetic mechanisms behind the development of the repertoire of specificities in B- and T-cell systems
- describe the maturation of B lymphocytes in the bone marrow and T-lymphocytes in the thymus and explain the mechanisms that cause tolerance to self.
- Explain effector mechanisms in the adaptive immune system and describe the different types of effector cells
- recognize or describe autoimmune diseases and their consequences
- recognize or describe the four types of hypersensitivity
- identify or describe infectious diseases, wherein the microorganism avoids the immune system
Content
- Introduction to the Immune System
- Cells and organs of the immune system
- Innate immunity including complement
- Antigens and antibodies
- Antigen-antibody interaction
- MHC and antigen processing and presentation
- TCR and T cell maturation
- BCR and B cell maturation
- Cytokines
- Cellular response, leukocyte activation
- Hypersensitivity, infections
- Immunedeficiencies, autoimmunity
- Transplantation, Tumor immunology
- Vaccines
Literature
Abul K. Abbas & Andrew H. H. Lichtman & Shiv Pillai. : Basic Immunology, Functions and Disorders of the Immune System, 6th Edition.
See Blackboard for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam a)
Timing
Tests
A compulsory project report
EKA
Assessment
Grading
Identification
Language
Examination aids
ECTS value
Additional information
Exam element a)
Timing
Prerequisites
Type | Prerequisite name | Prerequisite course |
---|---|---|
Examination part | Prerequisites for participating in the exam a) | N200006101, BMB512: Teoretical Immunology |
Tests
Written exam (3 hours)
EKA
Assessment
Grading
Identification
Language
Examination aids
ECTS value
Additional information
Indicative number of lessons
Teaching Method
At the faculty of science, the teaching is organized according to the three-phase model, ie. intro, the training and study phase.
- Introphase: 34 hours
- Training phase: 20 hours, of which: tutorial: 20 hours
The intro phase consists of lectures, where a brief introduction is given to the course topics and the path to competence acquisition as a supplement to the textbook, which the students are expected to study independently.
In the training phase, competencies within immunology are cultivated. In the tutorial classes, work is done on assignments that the students have prepared from home.
In the study phase, the students are expected to work independently on their project assignment as well as acquire relevant knowledge from the textbook. Students are expected to spend part of the study phase picking up on the training phase assignments as well as reserving a smaller portion for rehearsal up to the written exam.
Educational activities/study phase activities::
- Textbook reading to complenent lectures
- Independent synthesis of lecture and tutorial material
- Project work in groups
- Revision for exams