KE526: Applied heterocyclic chemistry
Study Board of Science
Teaching language: Danish, but English if international students are enrolled
EKA: N530025102
Assessment: Second examiner: External
Grading: 7-point grading scale
Offered in: Odense
Offered in: Spring
Level: Bachelor
STADS ID (UVA): N530025101
ECTS value: 5
Date of Approval: 05-11-2019
Duration: 1 semester
Version: Archive
Comment
- The course is co-read with: the corresponding master course KE823.
- You can not follow the course if KE823 is already taken.
- If
you plan to attend both Applied heterocyclic chemistry (KE526/KE823)
and Advanced organic synthesis (KE518/KE814) in your complete study
program, we recommend that you first attend KE526/KE823 or that you
attend the two courses simultaneously.
10006301(former UVA) is identical with this course description.
Entry requirements
Academic preconditions
Students who attend the course are expected to:
- be familiar with physical and organic chemistry including the structure and reactions of organic molecules as well as the concept of pH and thermodynamics.
- have experience with the use of reaction mechanisms
KE505 Organic chemistry, KE521 or KE528 Basic inorganic chemistry as well as KE523 Physical Chemistry A or KE537 Microscopic and macroscopic physical chemistry are expected.
Course introduction
The aim of the course is to make the students familiar with heterocyclic compounds and their importance in modern organic chemistry - including the synthesis of the most common heterocycles and their chemical properties.
The course is based primarily on the skills acquired in the second year course KE505 or equivalent with a systematic examination of the organic chemistry. The course is based on the fact that the students are in the third year of studies for a degree in chemistry, pharmacy, or chemical engineering, so that they can relate the course to other disciplines in chemistry, for example medicinal chemistry, spectroscopy, chemical engineering, physical chemistry, or inorganic chemistry.
In relation to the education competence profiles, the course has a particular focus on expanding and improving the students’ basis for planning organic syntheses and to apply reaction mechanisms within modern organic chemistry.
Expected learning outcome
The learning objectives of the course is that the student demonstrates the ability to:
- provide names for simple aliphatic and aromatic heterocycles
- use reaction mechanisms to predict the formation of selected heterocyclic compounds
- explain and account for the reactivity of selected heterocyclic compounds
- explain
examples of applications of selected heterocyclic compounds in for
example medicinal chemistry and supramolecular chemistry
Content
The following main topics are contained in the course:
- General nomenclature of heterocyclic compounds.
- Synthesis
and chemical properties of heterocyclic compounds including pyrroles,
furans, thiophenes, various five-membered heterocycles with several
heteroatoms, pyridines, diazines and annullated heterocycles. - Use of reactions mechanisms to account for the formation of heterocyclic compounds
- Examples of applications of heterocycles in for example medicinal chemistry and supramolecular chemistry.
Literature
John A. Joule and Keith Mills: Heterocyclic Chemistry at a Glance, 2nd Edition.
If you have a version of John A. Joule and Keith Mills: Heterocyclic Chemistry, 5th Edition, you can also use this.
Other material will be communicated via BlackBoard.
Examination regulations
Exam element a)
Timing
June
Tests
Oral exam
EKA
N530025102
Assessment
Second examiner: External
Grading
7-point grading scale
Identification
Student Identification Card
Language
Normally, the same as teaching language
Examination aids
A closer description of the exam rules will be posted under 'Course Information' on Blackboard.
ECTS value
5
Additional information
The examination form for re-examination may be different from the exam form at the regular exam.
Indicative number of lessons
Teaching Method
At the faculty of science, teaching is organized after the three-phase model ie. intro, training and study phase.
In the study phase, students are expected to work on their own with the textbook and examples herein. It also includes preparation of written exercises as a key element in the study phase. The students will independently search for and read research papers. The students are also expected to use part of the study phase to pick up on the content of training phase and to reserve a small amount of time for repetition for the oral exam.
- Self-study of the textbook
- Written hand-in exercises
- Search in scientific literature
- Repetition for the exam