SU517: Physiology and pharmacology for pharmacists – Module 2: Heart, vessels and kidneys

Study Board Pharmacy

Teaching language: Danish or English depending on the teacher
EKA: N560025102, N560025112
Assessment: Second examiner: Internal
Grading: 7-point grading scale, Pass/Fail
Offered in: Odense
Offered in: Spring
Level: Bachelor

STADS ID (UVA): N560025101
ECTS value: 5

Date of Approval: 29-10-2019


Duration: 1 semester

Version: Archive

Comment


Entry requirements

None

Academic preconditions

Students taking the course are expected to: Have knowledge of the basics of physics, chemistry and biochemistry

Course introduction

The aim of the course is to give students insight into the function
of specialized cells of the human body under normal physiological
conditions and in disease. This is important for being able to explain
the effect of a pharmacological treatment on specialized cell types
under normal physiological conditions and in disease. 

The
course is based on the knowledge acquired in module 1, i.e. SU516, and
provides a scientific basis for studying the modules 3 and 4 within the
‘Physiology and Pharmacology for Pharmacists’ course. It is also the
basis for the course on Clinical pharmacology and therapeutics, which
will be taught in the master's program.

With regard to the competence profile of the curriculum, it is the explicit focus of the course to:

Provide the competence to:
  • combine
    the various disciplines in the natural sciences with the more
    application-oriented medical disciplines, in particular for resolving
    pharmacological problems and for the development of new drugs 
Provide skills to:
  • acquire new knowledge effectively and independently and apply this knowledge in a critical way.
  • perform analyzes using scientific methodology
  • identify own deficits in knowledge and to structure own learning
Provide knowledge about:

  • the theories and methods within the discipline
  • knowledge acquisition and experimental methods in the pharmaceutical sciences and related fields.

Expected learning outcome

The learning objectives of the course are that the student demonstrates:
  • sufficient
    knowledge of the main molecular and cellular mechanisms for
    understanding structure and function of the organs (heart, vessels and
    kidneys).
  • ability to distinguish between the main molecular
    mechanisms of drugs acting on diseases affecting the heart, vessels, and
    kidneys.

Content

The following main topics are taught in the course:
  • Cardiovascular system: anatomy 
  • Cardiovascular system: physiology
    • Hemodynamics
    • Cardiac cycle
    • Cardiac output
    • ECG (electrocardiogram)
    • Control of blood flow and pressure
  • Cardiovascular system: pharmacology
    • Antihypertensives I (heart and vessels: inotropic drugs and vasodilators)
    • Atherosclerosis and lipid-lowering drugs
  • Renal system: anatomy
  • Renal system: physiology
    • Clearance
    • GFR (glomerular filtration rate) 
    • Fluid and electrolyte balance
    • Urine concentration
  • Renal system: pharmacology
    • Kidney pharmacokinetics
    • Drug administration
    • Pharmacogenetics
    • Drug interactions
    • Individualized therapy
    • Diuretics
    • Antihypertensive drugs II (antiarrhythmics and complex therapies)

Literature

Linda Costanzo: Physiology, 6th edition, Elsevier.

Rang & Dale: Pharmacology, 9th edition, Elsevier
See Blackboard for syllabus lists and additional literature references.

Examination regulations

Exam element a)

Timing

Spring

Tests

Ongoing evaluation: 2 written examinations overall assessment

EKA

N560025102

Assessment

Second examiner: Internal

Grading

7-point grading scale

Identification

Student Identification Card

Language

Normally, the same as teaching language

Duration

 2 hours each time

Examination aids

No aids. A closer description of the exam rules will be posted under \'Course Information\' on Blackboard.

ECTS value

4.75

Additional information

Exam element a) has overall assessment.
Reeksamen is held as an overall exam.


Exam element b)

Timing

Spring

Tests

Intro and oral presentation of case

EKA

N560025112

Assessment

Second examiner: Internal

Grading

Pass/Fail

Identification

Student Identification Card

Language

Normally, the same as teaching language

Examination aids

To be announced during the course.

ECTS value

0.25

Additional information

Reeksamen is held as an overall exam.

Indicative number of lessons

38 hours per semester

Teaching Method

The introduction phase consists of lectures, in which the students will get a brief introduction to the course topics and the way to achieve competences. This will be complemented by the study guide and the textbooks, which the students are expected to study independently.

During the training phase, the students will achieve competences in cardiovascular and renal anatomy, physiology and pharmacology. In the small classroom teaching, the students will work with assignments, which they will have to prepare at home. In cardio-lab, the students work independently with practical aspects of pharmacology.

In the study phase, students are expected to work independently with textbooks and examples and exercises herein. They are expected to work in small groups as regards elaboration and presentation of “case” work. Finally, students are expected to use part of the study phase to work on assignments of the training phase and do some repetition for the written exam.

  • Self-study of the textbook
  • Self-study after the introduction and training phase
  • Repetition in preparation of the exam

Teacher responsible

Name E-mail Department
Daniel Ketelhuth ketelhuth@health.sdu.dk IMM - Kardiovaskulær og Renal Forskning

Timetable

Administrative Unit

Fysik, kemi og Farmaci

Team at Educational Law & Registration

NAT

Offered in

Odense

Recommended course of study

Profile Education Semester Offer period