BMB512: Teoretical Immunology
Study Board of Science
Teaching language: Danish or English depending on the teacher
EKA: N200006112, N200006102
Assessment: Second examiner: None, Second examiner: External
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Autumn
Level: Bachelor
STADS ID (UVA): N200006101
ECTS value: 5
Date of Approval: 29-04-2019
Duration: 1 semester
Version: Archive
Comment
Entry requirements
Academic preconditions
Students taking the course are expected to:
- Have knowledge of basic molecular biology, biochemistry and protein chemistry
Course introduction
The aim of the course is to enable the student to understand and explain the immune system as a defense system, developed with the aim to protect against threats from the environment, mainly by preventing the entry and survival of potentially pathogenic microorganisms in the organism, which is important in regard to integrating immunological principles with more general biological, genetic and biochemical principles.
The course builds on the knowledge acquired in the courses BMB532 and BMB533 and gives an academic basis for studying the topic infection and immunity, as well as pathophysiology.
In relation to the competence profile of the degree it is the explicit focus of the course to:
- Give skills to interpret and evaluate current scientific literature in immunology at a basic level.
- Give knowledge and understanding of basic immunological mechanisms.
Expected learning outcome
The learning objectives of the course are that the student can demonstrate the ability to:
- describe the structure and individual elements of the innate and the adaptive immune system.
- explain the recognition mechanisms of the innate immune system and the consequences of its activation
- Explain the inflammatory response and describe the function of the key cytokines
- Explain the genetic mechanisms behind the development of the repertoire of specificities in B- and T-cell systems
- describe the maturation of B lymphocytes in the bone marrow and T-lymphocytes in the thymus and explain the mechanisms that cause tolerance to self.
- Explain effector mechanisms in the adaptive immune system and describe the different types of effector cells
- recognize or describe autoimmune diseases and their consequences
- recognize or describe the four types of hypersensitivity
- identify or describe infectious diseases, wherein the microorganism avoids the immune system
Content
The following main topics are contained in the course:
- Introduction to the Immune System
- Cells and organs of the immune system
- Innate immunity including complement
- Antigens and antibodies
- Antigen-antibody interaction
- MHC and antigen processing and presentation
- TCR and T cell maturation
- BCR and B cell maturation
- Cytokines
- Cellular response, leukocyte activation
- Hypersensitivity, infections
- Immunedeficiencies, autoimmunity
- Transplantation, Tumor immunology
- Vaccines
Literature
Abul K. Abbas & Andrew H. H. Lichtman & Shiv Pillai. : Basic Immunology, Functions and Disorders of the Immune System, 6th Edition.
See Blackboard for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam a)
Timing
Autumn
Tests
A compulsory project report
EKA
N200006112
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
0
Additional information
The prerequisite examination is a prerequisite for participation in exam element a)
Exam element a)
Timing
January
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam a) | N200006101, BMB512: Teoretical Immunology |
Tests
Written exam (3 hours)
EKA
N200006102
Assessment
Second examiner: External
Grading
7-point grading scale
Identification
Student Identification Card
Language
Normally, the same as teaching language
Examination aids
Not allowed, a closer description of the exam rules will be posted under 'Course Information' on Blackboard.
ECTS value
5
Additional information
The examination form for re-examination may be different from the exam form at the regular exam.
Indicative number of lessons
Teaching Method
Educational activities:
- Textbook reading to complenent lectures
- Independent synthesis of lecture and tutorial material
- Project work in groups
- Revision for exams