KE822: Organic chemical analysis and separation
Study Board of Science
Teaching language: Danish, but English if international students are enrolled
EKA: N540015112, N540015102
Assessment: Second examiner: None, Second examiner: External
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Autumn
Level: Master
STADS ID (UVA): N540015101
ECTS value: 5
Date of Approval: 14-04-2018
Duration: 1 semester
Version: Archive
Comment
10010401 (former UVA) is identical with this course description.
The course is co-read with KE510: Organic chemical analysis and separation (5 ECTS)
The course is co-read with KE510: Organic chemical analysis and separation (5 ECTS)
The course has a limited number of seats.
If there are vacant seats they will be assigned after these principles:
If there are vacant seats they will be assigned after these principles:
- Graduate students in medical chemistry, who are following the course in their module A
- Students who have passed KE505
Entry requirements
Academic preconditions
Students taking the course are expected to:
- have knowledge of NMR and IR spectroscopy and mass spectrometry.
- have detailed knowledge of organic chemistry, especially organic molecular structure and chemical reactions.
- have knowledge of simple inorganic molecules and salts as well as pH concept.
- have practical experience with laboratory work and general laboratory safety.
Course introduction
The aim of the course is to be trained in laboratory skills in organic chemistry, especially for workup and identification of organic compounds. The course forms therewith a basis for further chemistry and pharmacy courses and for experimental work within organic chemistry, medicinal chemistry or pharmacy. Furthermore, it forms the course background for pharmacy students to continue studies in medicinal chemistry and drug development, for chemistry students’ further study in organic synthesis and materials chemistry, and chemical engineering students’ further studies in process engineering.
The course builds on the knowledge acquired in the first-year course FF503 or equivalent with a basic level of general and organic chemistry and subsequent courses in organic chemistry KE505 and spectroscopy KE504. The course is based on the fact that the students are in the fourth year of studies for a degree in chemistry, pharmacy or chemical engineering, so that they can relate the course to other disciplines in chemistry, for example biochemistry, spectroscopy, chemical engineering, physical chemistry or inorganic chemistry.
In relation to the competence profile of the degree it is the explicit focus of the course to:
- Give authority to plan organic chemical laboratory work.
- Provide skills in identification of organic compounds.
- Provide skills and knowledge about the methods of separation of organic compounds.
- Provide skills in performing chemical synthesis on a small scale.
- Provide knowledge about the handling of the security aspects in an organic chemistry lab.
Expected learning outcome
The learning objectives of the course is that the student demonstrates the ability to:
- Use chemical methods for identification of organic compounds.
- Use spectroscopic methods for identification of organic compounds.
- Use chemical and column chromatographic separation techniques
- Perform chemical reactions on a small scale.
- Find reference data online.
- Using gas chromatography and HPLC.
- Estimate purity of a chemical.
Content
The following main topics are contained in the course:
- Separation of substance mixtures by extraction and preparative column chromatography.
- Making derivatives of organic compounds.
- Determination of functional groups and equivalent.
- HPLC and GLC analysis.
- Identification by MS, 1H and 13C NMR and IR spectra.
Literature
Exercise instructions placed on Blackboard.
See Blackboard for syllabus lists and additional literature references.
See Blackboard for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam a)
Timing
Autumn
Tests
Active participation in laboratory exercises and approval of two reports.
EKA
N540015112
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
Additional information
The prerequisite examination is a prerequisite for participation in exam element a)
Exam element a)
Timing
Autumn
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam a) | N540015101, KE822: Organic chemical analysis and separation |
Tests
Report
EKA
N540015102
Assessment
Second examiner: External
Grading
7-point grading scale
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
5
Additional information
The examination form for re-examination may be different from the exam form at the regular exam.
Indicative number of lessons
Teaching Method
Activities during the study phase:
- Self-study of methods for organic identification.
- Tutorial of electronic programs for literature search and handling of NMR and MS data.
- Identification of organic compounds on the basis of collected data.
- Preparation of reports of laboratory work and the identified organic compounds.