BMB822: Modern trends and technologies in molecular cell biology

• obtaining knowledge of theories and experimental methods based on the highest international research in biochemistry and molecular biology of the key areas listed above
• obtaining knowledge of biochemistry, molecular and cell biology and their interfaces to modern technology, health and environment

The course builds on the knowledge acquired in the courses Protein Chemistry (BMB506), Advanced Molecular Biology (BMB508) Metabolic and Hormonal regulation (BMB505), Fundamental Microbiology (BMB507) and Biomedical Microbiology (BMB510) and provides an academic basis for performing Master´s project at BMB.

In relation to the competence profile of the degree it is the explicit focus of the course to:

• Give the competence and skills to analyse and evaluate primary research in the fields of RNA biology, cell signaling and differentiation and -omics technologies through critical reviewing of original articles.
• Give skills to communicate research based knowledge, to identify and discuss scientific problems
• Give knowledge and understanding of the biological research areas at BMB as well as the technologies that are being used and developed at the institute.

• RNA biology: impact on health and disease.
• Post-transcriptional regulation in different organisms - from bacteria to humans.
• Methods and techniques in RNA biology, including RNA sequencing and RNA interference.
• Principles of eukaryotic cell signaling and cellular differentiation.
• Post-translational regulation of cell signaling and differentiation.
• Aberrant signaling processes in human diseases.
• Methods and techniques in various aspects of cell signaling and differentiation, including "genome-wide sequencing techniques" and mass spectrometry-based -omics techniques.