BMB803: Molecular Microbiology

Study Board of Science

Teaching language: English
EKA: N210014112, N210014102
Assessment: Second examiner: None, Second examiner: Internal
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Autumn
Level: Master

STADS ID (UVA): N210014101
ECTS value: 5

Date of Approval: 19-04-2018


Duration: 1 semester

Version: Archive

Comment

01016901 (former UVA) is identical with this course description. 

Entry requirements

None

Academic preconditions

Students taking the course are expected to:
  • Have knowledge of basic microbiology, biochemistry and molecular biology at the level of a bachelor's degree in biological science
  • Be able to use Powerpoint or similar presentation software
  • Be sufficiently fluent in English to give oral presentations and write reports


Course introduction

The aim of the course is to enable the student to obtain a broader knowledge and understanding of molecular processes in bacteria through a discussion of mechanisms leading to resistance to antimicrobial compounds. The course will give students experience in reading and understanding the latest research literature and communicating current results and concepts.

The course builds on the knowledge acquired in introductory courses in biochemistry, molecular biology, and microbiology (BMB507 and   BMB508, or similar) and contributes to the academic basis for a final year Masters thesis on a microbiological topic and employment in biotechnological industry or the health sector. 

In relation to the competence profile of the degree it is the explicit focus of the course to:
  • give the competence to independently acquire new knowledge at the highest professional level and integrate new knowledge with previous experience
  • give skills to critically evaluate original research findings and  presentation of research both orally and in writing
  • give knowledge of theoretical and experimental methods used in investigations of bacteria using molecular and structural biology

Expected learning outcome

The learning objective of the course is that the student demonstrates the ability to:
  • describe the main types of antimicrobial compounds used in treating infectious disease and explain their mechanism of action
  • describe the different mechanisms leading to resistance
  • critically evaluate original research articles on resistance to antimicrobial compounds and present seminars in English 

Content

The following main topics are contained in the course
  • Modern techniques used in molecular and structural biology
  • Major types of antibiotic and their mechanisms of action
  • Resistance against antibiotics 
  • Evolutionary theory applied to microbes as exemplified by the development of resistance to antibiotics
  • Antibiotics inhibiting ribosome function and mechanisms of resistance to these  
  • Structure and function of multidrug efflux pumps

Literature

See Blackboard for syllabus lists and additional literature references.

Examination regulations

Prerequisites for participating in the exam a)

Timing

Autumn

Tests

Satisfactory presentation of two research articles

EKA

N210014112

Assessment

Second examiner: None

Grading

Pass/Fail

Identification

Full name and SDU username

Language

Normally, the same as teaching language

Examination aids

To be announced during the course

Additional information

The prerequisite examination is a prerequisite for participation in exam element a)

Exam element a)

Timing

Autumn

Prerequisites

Type Prerequisite name Prerequisite course
Examination part Prerequisites for participating in the exam a) N210014101, BMB803: Molecular Microbiology

Tests

Final report with oral examination

EKA

N210014102

Assessment

Second examiner: Internal

Grading

7-point grading scale

Identification

Full name and SDU username

Language

Normally, the same as teaching language

Examination aids

To be announced during the course 

ECTS value

5

Additional information

The examination form for re-examination may be different from the exam form at the regular exam.

Indicative number of lessons

44 hours per semester

Teaching Method

The introductory phase comprises 12 hours of lecture where the main course themes are introduced. The skills training phase contains 32 hours of scheduled student presentations using Powerpoint or similar with subsequent discussion

Teacher responsible

Name E-mail Department
Stephen Douthwaite srd@bmb.sdu.dk

Additional teachers

Name E-mail Department City
Raymond P. Cox r.p.cox@bmb.sdu.dk

Timetable

Administrative Unit

Biokemi og Molekylær Biologi

Offered in

Odense

Recommended course of study

Profile Education Semester Offer period