KE506: Synthesis
Study Board of Science
Teaching language: Danish or English depending on the teacher, but English if international students are enrolled
EKA: N530004112, N530004102
Assessment: Second examiner: None, Second examiner: Internal
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Autumn
Level: Bachelor
STADS ID (UVA): N530004101
ECTS value: 5
Date of Approval: 13-04-2023
Duration: 1 semester
Version: Approved - active
Comment
The course is held in August.
Limited number of seats:
The course has a limited number of seats (18). Chemistry students, for whom the course is mandatory, are guaranteed a seat.
If there are vacant seats and more students registered, they will be assigned after:
If there are vacant seats and more students registered, they will be assigned after:
- Graduate students of medicinal chemistry.
- Students who have passed the course KE505 Organic chemistry.
A waiting list may be established.
Entry requirements
The laboratory exercises, prerequisite examination b) (EKA N530021112), in the course KE505: Organic chemistry (10 ECTS) must be followed and passed.
Academic preconditions
Students who attend the course are expected to
- have knowledge of general chemistry and systematic organic chemistry including organic structure and reactions.
- be able to apply organic reaction mechanisms
- have practical experience with laboratory work including basic organic synthesis and general laboratory safety in a synthesis laboratory.
Participant limit
Course introduction
The aim of the course is to give the students a detailed knowledge about unit operations used in a synthetic laboratory. Thus, the objective of the course is to provide the students with practical knowledge that forms the basis of the completion of a bachelor project within synthetic chemistry and for further studies.
The course is based primarily on the skills acquired in the course KE505 Organic chemistry (10 ECTS) or equivalent with a systematic treatment of organic chemistry. The course is based on the fact that the students are in the third or fourth year of studies for a degree in chemistry, pharmacy, or chemical engineering, so that they can relate the course to other disciplines in chemistry, for example spectroscopy, chemical engineering, physical chemistry, or inorganic chemistry.
In relation to the education competence profiles, the course has a particular focus on expanding and improving the experimental basis for chemical synthesis including the handling of safety aspects in an organic synthesis laboratory.
Expected learning outcome
The learning objective of the course is that the student demonstrates the ability to:
- relate theoretical knowledge of organic reactions and reaction mechanisms to carry out practical organic synthesis
- carry out synthesis
- carry out limited multi-step syntheses
- carry out synthesis under an inert atmosphere
- describe and use different purification techniques
- determine the purity of the compounds synthesized using analytical and spectroscopic methods
- conduct literature searches in Reaxys
- explain and apply safe behavior in a synthetic laboratory
Content
The following main topics are contained in the course:
- Precautions against accidents in the laboratory
- Secure behavior in a synthetic laboratory
- Literature search in Reaxys
- Planning of synthetic work
- Different unit operations used in a synthetic laboratory
- Preparation of selected organic and inorganic compounds
- Safe behavior in a synthetic laboratory
Literature
Mikael Begtrup, Jan Becher og Mogens Brøndsted: Håndbog i organisk synteseteknik, Gyldendal, 2011.
Jan O. Jeppesen, Stinne W. Hansen, Steffen Bähring, Niels Svenstrup & Jesper Lau: Institut for Fysik og Kemi, Syddansk Universitet, 2010.
See itslearning for syllabus lists and additional literature references.
Examination regulations
Prerequisites for participating in the exam a)
Timing
August
Tests
Participation in laboratory exercises
EKA
N530004112
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
0
Additional information
Attendance at laboratory exercises and approval of compulsory reports with theoretical questions.
The prerequisite examination is a prerequisite for participation in exam element a) .
The prerequisite examination is a prerequisite for participation in exam element a) .
Exam element a)
Timing
September
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam a) | N530004101, KE506: Synthesis |
Tests
Oral examination
EKA
N530004102
Assessment
Second examiner: Internal
Grading
7-point grading scale
Identification
Student Identification Card
Language
Normally, the same as teaching language
Examination aids
To be announced during the course
ECTS value
5
Additional information
At the exam, the student should present a PowerPoint presentation.
Re-examination right after the end of the course.
Re-examination right after the end of the course.
Indicative number of lessons
Teaching Method
At the faculty of science, teaching is organized after the three-phase model, ie. intro, training and study phase.
The teaching activities are implemented as an estimated suggested allocation of the workload of an average student as follows:
- Training phase: 48 lab hours.
Since the course is a continuation of the laboratory exercises in KE505 – Organic Chemistry, there is no definite intro phase in the course, but the students are expected to repeat the skills they have acquired in the laboratory part of KE505, and prepare thoroughly before the course starts.
In the training phase, competences are cultivated within the central parts of the course - especially the ability to relate theoretical knowledge of organic reactions and reaction mechanisms to the practical carrying out of organic synthesis. In the laboratory exercises, the students work independently with practical exercises in chemical synthesis, but differentiated teaching is practiced to some extent depending on the student's practical and theoretical skills.
In the study phase, the students are expected to work on their own with the textbook in Organic Chemistry and relevant examples herein. This also includes both laboratory reports and report schemes as key elements in the study phase, and the students can expect feedback on both from a teacher. The students are also expected to use part of the study phase to pick up on the content of the training phase and to reserve a small amount of time for repetition for the oral exam.
Teacher responsible
Timetable
Administrative Unit
Team at Educational Law & Registration
Offered in
Recommended course of study
Transition rules
Transitional arrangements describe how a course replaces another course when changes are made to the course of study.
If a transitional arrangement has been made for a course, it will be stated in the list.
See transitional arrangements for all courses at the Faculty of Science.