KE823: Applied heterocyclic chemistry
Comment
DISCONTINUED - last offered Spring 2021. New course KE835.
- If there are fewer than 12 students enrolled, the course may. be held with another teaching form.
- The course is co-read with the corresponding bachelor course KE526
- If you plan to attend both Applied heterocyclic chemistry (KE526/KE823) and Advanced organic synthesis (KE518/KE814) in your complete study program, we recommend that you first attend KE526/KE823 or that you attend the two courses simultaneously.
Entry requirements
Academic preconditions
Students who attend the course are expected to:
- be familiar with physical and organic chemistry including the structure and reactions of organic molecules as well as the concept of pH and thermodynamics.
- have experience with the use of reaction mechanisms
- KE505 Organic chemistry, KE521 or KE528 Basic inorganic chemistry as well as KE523 Physical Chemistry A or KE537 Microscopic and macroscopic physical chemistry are expected.
Course introduction
Expected learning outcome
The learning objectives of the course is that the student demonstrates the ability to:
- provide names for simple aliphatic and aromatic heterocycles
- use reaction mechanisms to predict the formation of selected heterocyclic compounds
- explain and account for the reactivity of selected heterocyclic compounds
- explain and discuss the applications of selected heterocyclic compounds inmedicinal chemistry and supramolecular chemistry
Content
- General nomenclature of heterocyclic compounds.
- Synthesis
and chemical properties of heterocyclic compounds including pyrroles,
furans, thiophenes, various five-membered heterocycles with several
heteroatoms, pyridines, diazines and annullated heterocycles. - Use of reactions mechanisms to account for the formation of heterocyclic compounds
- Examples of applications of heterocycles in for example medicinal chemistry and supramolecular chemistry.
Literature
John A. Joule and Keith Mills: Heterocyclic Chemistry at a Glance, 2nd Edition.
If you have a version of John A. Joule and Keith Mills: Heterocyclic Chemistry, 5th Edition, you can also use this.
Other material will be communicated via itslearning.
Examination regulations
Exam element a)
Timing
Tests
Oral exam
EKA
Assessment
Grading
Identification
Language
Duration
Examination aids
To be announced during the course
ECTS value
Additional information
Indicative number of lessons
Teaching Method
At the faculty of science, teaching is organized after the three-phase model ie. intro, training and study phase.
In the study phase, students are expected to work on their own with the textbook and examples herein. It also includes preparation of written exercises as a key element in the study phase. The students will independently search for and read research papers. The students are also expected to use part of the study phase to pick up on the content of training phase and to reserve a small amount of time for repetition for the oral exam.
Activities during the studyphase:
- Self-study of the textbook
- Written hand-in exercises
- Search in scientific literature
- Repetition for the exam