FA507: Instrumental pharmaceutical analysis
Study Board Pharmacy
Teaching language: Danish or English depending on the teacher
EKA: N560024112, N560024122, N560024102
Assessment: Second examiner: None, Second examiner: External
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Spring
Level: Bachelor
STADS ID (UVA): N560024101
ECTS value: 10
Date of Approval: 27-10-2025
Duration: 1 semester
Version: Approved - active
Internal Course Code
Comment
The course is partly co-taught with KE530: Quantitative Analytical Chemistry and K-PTE4-U1 offered by Department of Green Technology (IGT).
Entry requirements
The course cannot be followed by students who have taken KE504: Analytical spectroscopy (5 ECTS), og KE530.
Academic preconditions
Students taking the course are expected to have completed FA501, KE557, KE558, KE521 and KE538 and participate in KE505 in the same period of time as this course at the latest.
The course builds on the knowledge acquired in the basic pharmacy course (FA501) and the basic subjects in chemistry (KE557, KE558), physics (FY528) and mathematics (MM556) in the first year of study.
The course provides the professional basis for using instrumental analytical methods in further studies.
Course introduction
The purpose of the course is for the student to gain knowledge of instrumental methods for qualitative and quantitative analysis, so that the student is able to solve analytical problems, including critical assessment of chosen analysis technique, implementation of method development, optimization and validation, independent execution of data processing incl. to use statistical methods and clear and precise reporting of analytical results. In addition, the student must know and apply analytical guidelines (GLP, ICH, Ph.Eur.) and assess relevant professional literature.
Expected learning outcome
In order to achieve the purpose of the course, the learning objective for the course is for the student to demonstrate the ability to:
- be able to critically assess and apply analytical instrumental methods to solve qualitative and quantitative analytical pharmaceutical problems and to take into account official monographs (Ph.Eur.) and guidelines (ICH, GLP) as well as scientific literature (competences),
- be able to perform and optimize analytical methods, perform quantitative determination (calibration, standards), calculate validation parameters including precision, accuracy, selectivity, detection limit, quantification limit, separation and column parameters, use statistical methods and report test results in easy-to-understand, precise and correct language (skills) and
- know central concepts and principles of the analytical process (validation, statistical analysis methods), spectroscopic methods incl. for structural analysis (UV/Vis, IR, NMR, MS), chromatographic separation methods (HPLC, TLC, GC, SEC, AAS) as well as coupling separation methods with common detection methods (knowledge). Make a critical assessment of a given analysis technique with focus on optimization and validation
- Interpret results using statistical analyses and tests by building on the competences in [R] from earlier courses
- Carry out analyses using HPLC and GC
- Work sensibly and safely in an analytical chemistry laboratory
Content
The course contains the following main subject areas:
- General chromatographic concepts as well as method development, optimization and validation. Influence of the mobile and stationary phases, as well as column selection
- Chromatographic separation methods (HPLC, TLC, GC, SEC, AAS)
- Spectroscopic methods incl. for structural analysis (UV/Vis, IR, NMR, MS)
- Quantification principles
- Statistical distribution functions and probability
- Hypothesis testing of one or two variables (t-test and paired t-test)
- One-way and multi-way analysis of variance
- Linear regression analysis
- Experimental trial design
- Method validation and statistical analyses
- Uncertainty budgets
- GLP (Good Laboratory Practice)
- Definition of national and international standards
- Definition of accreditation and certification
- Definition of GMP (Good Manufacturing Practice), GLP (Good Laboratory Practice) and other Good Practices
Literature
Examination regulations
Prerequisites for participating in the exam a)
Timing
Spring
Tests
Participation in lab exercises and E-hours
EKA
N560024112
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course.
ECTS value
0
Additional information
Participation in lab exercises and E-hours (at least 80 % for both).
The prerequisite examination is a prerequisite for participation in exam element a) og b).
The prerequisite examination is a prerequisite for participation in exam element a) og b).
Exam element a)
Timing
Spring
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam a) | N560024101, FA507: Instrumental pharmaceutical analysis |
Tests
Reports and exercises
EKA
N560024122
Assessment
Second examiner: None
Grading
Pass/Fail
Identification
Full name and SDU username
Language
Normally, the same as teaching language
Examination aids
To be announced during the course.
ECTS value
2
Exam element b)
Timing
June
Prerequisites
| Type | Prerequisite name | Prerequisite course |
|---|---|---|
| Examination part | Prerequisites for participating in the exam a) | N560024101, FA507: Instrumental pharmaceutical analysis |
Tests
Written examination
EKA
N560024102
Assessment
Second examiner: External
Grading
7-point grading scale
Identification
Student Identification Card - Exam number
Language
Normally, the same as teaching language
Duration
4 hours
Examination aids
All common aids are allowed e.g. books, notes and computer programmes which do not use internet etc.
Physical calculators, the internet, and any form of generative artificial intelligence are not allowed during the exam. However, you may visit the course site in itslearning to fill in the MCQ test and to open system "DE-Digital Exam". If you wish to use course materials from itslearning, you must download the materials to your computer no later than the day before the exam. During the exam you cannot be sure that all course materials is accessible in itslearning.
ECTS value
8
Additional information
The exam paper is MCQ format and free format. The MCQ part is handed out in the system DE-Digital Exam.
With 10 or fewer students, the format of the rexam will be an oral exam. The exam will be 25 minutes (incl. voting) with 25 minutes of preparation.
Indicative number of lessons
Teaching Method
Planned lessons:
Total number of planned lessons: 100
Hereof:
Common lessons in classroom/auditorium: 44
Team lessons in classroom: 44
Team lessons in laboratory: 12
The teaching consists of lectures delivered to the entire cohort. These provide an overview of the course topics, including a brief introduction and contextualization. Student engagement during lectures is facilitated through, for example, the use of Poll Everywhere, which enables students to respond to or pose questions regarding the material presented. This approach incentivizes participation while preserving student anonymity.
Total number of planned lessons: 100
Hereof:
Common lessons in classroom/auditorium: 44
Team lessons in classroom: 44
Team lessons in laboratory: 12
The teaching consists of lectures delivered to the entire cohort. These provide an overview of the course topics, including a brief introduction and contextualization. Student engagement during lectures is facilitated through, for example, the use of Poll Everywhere, which enables students to respond to or pose questions regarding the material presented. This approach incentivizes participation while preserving student anonymity.
The cohort is divided into smaller groups that participate in both seminar sessions and mandatory laboratory exercises. The seminar sessions are designed to facilitate active learning, whereby students, through active participation, work with the course content. Through, for instance, problem-solving activities, conducted either collaboratively or individually, students are encouraged to advance along the taxonomic hierarchy of learning.
During the laboratory sessions, students work in larger groups to perform practical exercises within the disciplinary scope of the course. The outcome of these activities includes written reports, which constitute a component of the assessment of student learning.
Other planned activities:
Students engage with study-supporting activities that enhance their ability to participate actively in the teaching. Such activities may include reading the textbook and other relevant literature, consolidating lecture content, or exercises requiring the production of outputs in [R], Word, or similar programs for inclusion in reports. Furthermore, cooperative learning will be integrated into selected assignments.
Teacher responsible
Additional teachers
| Name | Department | City | |
|---|---|---|---|
| Mathias Porsmose Clausen | mpc@igt.sdu.dk | Institut for Grøn Teknologi | Odense |
| Michael Petersen | mip@sdu.dk | Kemi og Farmaci | Odense |
Timetable
Administrative Unit
Team at Registration
Offered in
Recommended course of study
Transition rules
Transitional arrangements describe how a course replaces another course when changes are made to the course of study.
If a transitional arrangement has been made for a course, it will be stated in the list.
See transitional arrangements for all courses at the Faculty of Science.